Cat#:PA-3745F;Product Name:Goat Anti-Human C4 Antibody;Synonym:Acidic C4; Acidic complement C4; Basic C4; Basic complement C4; C4 Anaphylatoxin; C4 propeptide; Rodgers Form Of C4; Complement-C4; C4; C4; CO4_HUMAN; Complement Component 4;Background:C4 consists of three polypeptide chains (alpha, molecular weight 95 kDa, beta, molecular weight 75 kDa and gamma, molecular weight 33 kDa) and is usually present in serum at 200-600mg/L. It is a protein of the classical complement pathway. When activated by C1s, a peptide C4a is released and the generated C4b binds C2 which is in turn cleaved by C1s to produce the classical pathway C3 convertase, namely C4b2a. C4b also has opsonin activity and binds to macrophages and neutrophils via their CR1 receptor.;Description:Goat Anti-Human C4 Polyclonal Antibody;Formulation:Liquid Solution;Host Species:Goat;Species Reactivity:Human;Isotype:IgG1;Application:TIA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;