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Mouse Anti-WT1 (Wilms' Tumor) Antibody Online Inquiry

Product Name:Mouse Anti-WT1 (Wilms' Tumor) Antibody
Synonym: Wilms tumor 1; GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1; Wilms tumor protein; amino-terminal domain of EWS|last three zinc fingers of the DNA-binding domain of WT1; OTTHUMP00000037553; OTTHUMP00000037554; OTTHUMP00000037555; OTTHUMP00000037556; OTTHUMP00000238018
Gene Introduction: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Description: Mouse Anti-WT1 (Wilms' Tumor) Monoclonal Antibody
Formulation: Liquid Solution
Host Species: Mouse
Species Reactivity: Human
Clone#: CD.7E-J4
Isotype: IgG1, Kappa
Application: IHC
Usage: For Lab Research Use Only
Storage: Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles

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