Cat#:RP-1839M;Product Name:Recombinant Mouse IL-22 Antagonist Protein;Synonym:IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23.;Description:Interleukin-22 Antagonist Mouse Recombinant produced in E.coli is a single, non-glycosylated homodimeric polypeptide chain containing 147 amino acids and having a total molecular mass of 16.7 KDa. The Mouse IL-22 Antagonist is purified by proprietary chromatographic techniques.;Source:E.coli;AA Sequence:The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Val-Asn.;Purity:Greater than 98.0% as determined by: (a) Gel filtration chromatography under non-denaturing conditions. (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.;Bioactivity:IL-22 E117A mutant is capable of full inhibition of STAT3 phosphorylation induced by mouse interleukin 22 in HepG cells. Its affinity toward immobilized mIL-22 receptor a1 extracellular domain (mIL-22 Ra1-ECD) or IL-22 binding protein is similar to the no;Formulation:IL-22 Antagonist Mouse is lyophilized from a concentrated (1mg/ml) solution in water containing NaHCO3.;Stability:Recombinant Proteins are stable for up to 1 year from date of receipt at -70℃;Reconstitution:It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.;Storage:Lyophilized Interleukin-22 Mouse Antagonist?although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL22?Antagonist?should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.;