Cat#:RP-2636HAT;Product Name:Recombinant Human RXR-alpha (Retinoid x receptor) Protein;Synonym:Retinoid X receptor alpha;Description:The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. The human recombinant RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over produced in E.coli. This recombinant protein was purified using our unique column purification methods.;Source:E.coli;AA Sequence:111-228aa;Molecular Characterization:13.6 kDa;Purity:Greater than 95% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human RXR-alpha (Retinoid x receptor) Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human RXR-alpha (Retinoid x receptor) protein was supplied in 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol;Storage:Recombinant Human RXR-alpha (Retinoid x receptor) Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;