Cat#:RP-2430HAT;Product Name:Recombinant Human PTH Protein;Description:The human recombinant parathyroid hormone(hPTH) is an 84 amino acid residue peptide and one of the main regulators in maintenance of calcium homeostasis. It acts primarily on kidney and bone cells stimulating calcium back resorption or calcium mobilization, respectively. The whole mechanism is still under discussion, but low-dose hPTH triggers cyclic AMP-dependent protein kinase in some populations of bone cells bearing PTH receptors, which stimulates the proliferation of osteoblasts. The human recombinant parathyroid hormone(amino acids 32-115) was overproduced in E. coli. This recombinant protein was purified to apparent homogeneity using our unique column purification methods;Source:E.coli;AA Sequence:32-115aa;Molecular Characterization:9.55 kDa;Purity:Greater than 95% by SDS-PAGE;Endotoxin:< 1.0 EU per ug of protein as determined by LAL method.;Bioactivity:Measured by its ability to induce cAMP accumulation in MC3T3/E1 mouse preosteoblast cells. The ED50 for this effect is less than or equal to 50 ng/ml.;Formulation:Liquid Solution;Stability:Recombinant Human PTH Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human PTH protein was supplied in phosphate-buffered Saline(pH 7.4) containing 2 mM EDTA;Storage:Recombinant Human PTH Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;