Cat#:RP-1958HAT;Product Name:Recombinant Human NANOG Protein;Synonym:Nanog homeobox;Description:Nanog homeobox, also known as nanog, is a member of the homeobox family of DNA binding transcription factors that has been shown to maintain pluripotency of embryonic stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.;Source:E.coli;AA Sequence:1-305aa;Molecular Characterization:34.6 kDa;Purity:Greater than 80% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human NANOG Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human NANOG protein was supplied in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol;Storage:Recombinant Human NANOG Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;