Cat#:RP-728HAT;Product Name:Recombinant Human CSF1 Protein;Synonym:Macrophage colony-stimulating factor 1;Background:Gene ID: 1435; CSF1, the full name is colony stimulating factor 1. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011];Description:The human recombinant CSF1, fused with His tag at C-terminus, was produced in insect cell. This recombinant protein was purified using our unique purification methods.;Source:Baculovirus;AA Sequence:33-255aa;Molecular Characterization:26.1kDa;Purity:Greater than 95 % by SDS-PAGE;Endotoxin:< 1.0 EU per ug of protein as determined by LAL method.;Bioactivity:Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cell. The ED50 for this effect is less or equal to 3 ng/ml.;Formulation:Liquid Solution;Stability:Recombinant Human CSF1 Protein was stable up to 1 year from date of receipt at -70℃;Host Species:Human;Concentration:0.25mg/mL;Storage Buffer:Recombinant Human CSF1 protein was supplied in PBS (pH 7.4) containing 10% glycerol;Storage:Recombinant Human CSF1 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;References:CSF1 is involved in breast cancer progression through inducing monocyte differentiation and homing. Ding J, et al. Int J Oncol, 2016 Nov. PMID 27599777;