Cat#:RP-1634HAT;Product Name:Recombinant Human KIR3DL1(Cytoplasmic tail) Protein;Synonym:Killer cell immunoglobulin-like receptor 3DL1;Description:The three Ig-domain from of inhibitory killer cell Ig-like receptor 1(KIR3DL1,NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DL1 recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs(ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His tag fusion protein of KIR3DL1 cytoplasmic tail(361-444aa) was overexpressed as insoluble protein aggregates(inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer;Source:E.coli;AA Sequence:361-444aa;Molecular Characterization:15 kDa;Purity:Greater than 95% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human KIR3DL1(Cytoplasmic tail) Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human KIR3DL1(Cytoplasmic tail) protein was supplied in 25 mM Tris-HCl (pH7.5) 100mM NaCl;Storage:Recombinant Human KIR3DL1(Cytoplasmic tail) Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;