Cat#:RP-1577HAT;Product Name:Recombinant Human Interleukin-18 Protein;Description:Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-gamma)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was produced in E.coli and purifed using the chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.;Source:E.coli;AA Sequence:37-193 aa;Molecular Characterization:18.3kDa;Purity:Greater than 95% by SDS-PAGE;Endotoxin:< 1.0 EU per ug of protein as determined by LAL method.;Bioactivity:Measured by its ability to induce IFN-gamma secretion using KG-1 human myeloid leukemia cells in the presence of TNF-alpha. The ED50 for this effect is less or equal to 850 ng/ml.;Formulation:Liquid Solution;Stability:Recombinant Human Interleukin-18 Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human Interleukin-18 protein was supplied in PBS (pH 7.4);Storage:Recombinant Human Interleukin-18 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;