Cat#:RP-1165HAT;Product Name:Recombinant Human GDF-5 Protein;Synonym:Growth differentiation factor 5;Description:Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused with His tag at N Terminus, was expressed as insoluble protein aggregate in E.coli. This recombinant protein was purified using the chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.;Source:E.coli;AA Sequence:382-501aa;Molecular Characterization:15.8 kDa;Purity:Greater than 95% by SDS-PAGE;Endotoxin:< 1.0 EU per ug of protein as determined by LAL method.;Formulation:Liquid Solution;Stability:Recombinant Human GDF-5 Protein was stable up to 1 year from date of receipt at -70℃;Concentration:0.5mg/mL;Storage Buffer:Recombinant Human GDF-5 protein was supplied in 10 mM Sodium citrate pH 3.5, 10% glycerol;Storage:Recombinant Human GDF-5 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;
Growth differentiation factor 5(GDF-5) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein plays a role in chondrogenesis and chondrocyte metabolism, tendon and ligament tissue formation, and bone repair. It also increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease. GDF-5, fused with His tag at N Terminus, was expressed as insoluble protein aggregate in E.coli. This recombinant protein was purified using the chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Source:
E.coli
AA Sequence:
382-501aa
Molecular Characterization:
15.8 kDa
Purity:
Greater than 95% by SDS-PAGE
Endotoxin:
< 1.0 EU per ug of protein as determined by LAL method.
Formulation:
Liquid Solution
Stability:
Recombinant Human GDF-5 Protein was stable up to 1 year from date of receipt at -70℃
Concentration:
0.5mg/mL
Storage Buffer:
Recombinant Human GDF-5 protein was supplied in 10 mM Sodium citrate pH 3.5, 10% glycerol
Usage:
For Lab Research Use Only
Storage:
Recombinant Human GDF-5 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.