Cat#:CREB1-005RPH;Product Name:Recombinant Human CREB1 Protein;Synonym:CREB1; cAMP responsive element binding protein 1; CREB; CREB-1 ;Background:Gene ID: 1385. CREB1, the full name is cAMP responsive element binding protein 1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016];Description:Recombinant Human CREB1 protein is a full-length protein( AAH10636, 1 a.a. - 341 a.a.). The CREB1 recombinant protein was fused with a GST tag at N-terminal.;Source:Wheat Germ (in vitro);AA Sequence:MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQSSCKDLKRLFSGTQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNHVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAAREC;Molecular Characterization:63.25kDa;Purity:12.5% SDS-PAGE Stained with Coomassie Blue.;Formulation:Liquid Solution;Host Species:Human;Storage:Store the recombinant human CREB1 protein at -80°C. Aliquot to avoid repeated freezing and thawing.;Usage:For Lab Research Use Only;Supplied in:50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.;References:Knockdown of CREB1 inhibits tumor growth of human gastric cancer in vitro and in vivo. Rao M, et al. Oncol Rep, 2017 Jun. PMID 28498439;