Cat#:RP-573HAT;Product Name:Recombinant Human CEBP-alpha (bZIPregion residues) Protein;Synonym:CCAAT/enhancer binding protein a;Description:CCAAT/enhancer binding protein(C/EBP) alpha is a family of transcription factors that all contain a highly conserved, basic-leucine zipper domain at the C-terminus that is involved in dimerization and DNA binding. C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP family consist of several related proteins, C/EBP alpha, beta, gamma,delta, that form homodimers and that form heterodimers with each other. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein; a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. C/EBPs differ significantly in their physiological functions and in their downstream target genes. For example, mice lacking C/EBP alpha die shortly after birth due to severe hypoglycemia and the absence of glycogen storage in liver, whereas knockout of C/EBPbeta causes defects in female reproduction The bZip region of CEBP-alpha (residues 270-358)was produced in E.coli. This recombinant protein was purified by ion-exchange chromatography and FPLC gel-filtration chromatography.;Source:E.coli;AA Sequence:270-358aa;Molecular Characterization:14.5kDa;Purity:Greater than 95% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human CEBP-alpha (bZIPregion residues) Protein was stable up to 1 year from date of receipt at -70℃;Concentration:1mg/mL;Storage Buffer:Recombinant Human CEBP-alpha (bZIPregion residues) protein was supplied in. 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol.;Storage:Recombinant Human CEBP-alpha (bZIPregion residues) Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;