Cat#:RP-023HAT;Product Name:Recombinant Human ABI3 Protein;Synonym:ABI family member 3;Description:ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.;Source:E.coli;AA Sequence:1-366aa;Molecular Characterization:41.4 kDa;Purity:Greater than 85% by SDS-PAGE;Formulation:Liquid Solution;Stability:Recombinant Human ABI3 Protein was stable up to 1 year from date of receipt at -70℃;Concentration:0.5mg/mL;Storage Buffer:Recombinant Human ABI3 protein was supplied in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol;Storage:Recombinant Human ABI3 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;