Cat#: | RP-728HAT |
Product Name: | Recombinant Human CSF1 Protein |
Synonym: | Macrophage colony-stimulating factor 1 |
Gene Introduction: | Gene ID: 1435; CSF1, the full name is colony stimulating factor 1. The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
Description: | The human recombinant CSF1, fused with His tag at C-terminus, was produced in insect cell. This recombinant protein was purified using our unique purification methods. |
Source: | Baculovirus |
AA Sequence: | 33-255aa |
Molecular Characterization: | 26.1kDa |
Purity: | Greater than 95 % by SDS-PAGE |
Endotoxin: | < 1.0 EU per ug of protein as determined by LAL method. |
Bioactivity: | Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cell. The ED50 for this effect is less or equal to 3 ng/ml. |
Formulation: | Liquid Solution |
Stability: | Recombinant Human CSF1 Protein was stable up to 1 year from date of receipt at -70℃ |
Host Species: | Human |
Concentration: | 0.25mg/mL |
Storage Buffer: | Recombinant Human CSF1 protein was supplied in PBS (pH 7.4) containing 10% glycerol |
Usage: | For Lab Research Use Only |
Storage: | Recombinant Human CSF1 Protein can be stored at +4℃for 1-2 weeks. It is recommended that the recombinant protein be aliquoted for optimal storage at -20 or -70℃. Please avoid repeated freeze-thaw cycles. |
References: | CSF1 is involved in breast cancer progression through inducing monocyte differentiation and homing. Ding J, et al. Int J Oncol, 2016 Nov. PMID 27599777 |