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Recombinant Human Pyruvate Kinase M2 / PKM2 Protein Online Inquiry

Product Name:Recombinant Human Pyruvate Kinase M2 / PKM2 Protein
Synonym: Pyruvate kinase PKM, CTHBP, OIP-3, THBP1
Gene Introduction: PKM, the full name is pyruvate kinase M1/2. Gene ID: 5315. This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
Description: Recombinant Human Pyruvate kinase M2 Protein is produced in E.coli and the target gene encoding Ser2-Pro531 is expressed with a His tag at the N-terminus.
Source: E. coli
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: < 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation: Recombinant Human Pyruvate Kinase M2/PKM2 Protein was supplied as a 0.2 μm filtered solution of PBS, pH7.0, 10% glycerol.
Stability: Recombinant Human Pyruvate Kinase M2/PKM2 Protein is stable for up to 1 year from date of receipt at -70℃.
Usage: For Lab Research Use Only
Storage: Store Recombinant Human Pyruvate Kinase M2/PKM2 Protein below -20°C, stable for 6 months after receipt. Please avoid repeated freeze-thaw cycles.
References: LincRNA-p21 suppresses development of human prostate cancer through inhibition of PKM2. Wang X, et al. Cell Prolif, 2017 Dec. PMID 28994148

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