Cat#:SRC-003RPH;Product Name:Recombinant Rous Sarcoma Virus SRC Protein(GST Tag);Synonym:SRC; ASV; SRC1; c-SRC; p60-Src;Background:Gene ID: 6714.Full name is Homo sapiens SRC proto-oncogene, non-receptor tyrosine kinase (SRC), transcript variant 1. SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates.Src is a member of the tyrosine kinase family that was originally identified as the oncogene of Rous sarcoma virus.The Src family of tyrosine kinase is involved in a variety of receptor-induced signal transduction pathways. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.;Description:Recombinant full-length Rous sarcoma virus SRC protein, expressed from baculovirus in Sf9 insect cells was fused with a GST tag at N-terminal.;Source:Sf9 insect cells;Molecular Characterization:85kDa;Purity:Greater than 90% as determined by densitometry.;Bioactivity:The bioactivity of recombinant SRC protein was deter-mined to be 116 nmol/min/mg.;Formulation:Recombinant SRC Protein was supplied in 50mM TRIS-HCl, pH 7.5, containing 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF and 25% glycerol.;Storage:The recombinant src protein is shipped using dry ice. Store this recombinant protein at -70℃;Usage:For Research Use Only!;References:Daisuke Okutani, et al. Src protein tyrosine kinase family and acute inflammatory responses. American Journal of Physiology-Lung Cellular and Molecular Physiology Vol. 291;