Cat#:ADV-3008EK;Product Name:Rat dipeptidyl peptldase Ⅳ, DPPⅣ ELISA Kit;Size:96T, 5×96T, 10×96T;Sample:Serum, Plasma, Tissue Homogenates;Synonym:Dpp4; Cd26; Dipeptidyl peptidase 4; Bile canaliculus domain-specific membrane glycoprotein; Dipeptidyl peptidase IV; DPP IV; GP110 glycoprotein; T-cell activation antigen CD26; CD antigen CD26;Description:This rat DPP4 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of rat DPP4 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the DPP4 levels in the sample and is measured at 450 nm through a microplate reader. DPP4, also called CD26, is a serine protease that is widely distributed in various organs and cells. Through regulating energy metabolism, inflammation, and immune function, DPP4 is involved in various physiological and pathological processes such as inflammation, energy metabolism, immune regulation, cell adhesion, and apoptosis. During the COVID-19 global pandemic, DPP4 was found to be an important marker that may play a significant role in disease progression. DPP4 is also a surface marker expressed in senescent cells. DPP4 has also been demonstrated to be associated with CD8+ T cell co-stimulation, B cell activation, macrophage polarization, and NK cell proliferation, playing an emerging role in modulating immune functions. Regarding its role in the immune system, DPP4 was shown to participate in the pathogenesis of autoimmune diseases like rheumatoid arthritis, inflammatory bowel disease as well as graft-versus-host disease (GVHD).;Species Reactivity:Rat;Usage:For Research Use Only;Detection Principle:Sandwich ELISA;Detection Range:0.78 ng/mL - 50 ng/mL;Sensitivity:0.195 ng/mL;