Cat#:ADV-3262EK;Product Name:Human Eotaxin 2/CCL24 ELISA Kit;Size:96T, 5×96T, 10×96T;Sample:Serum, Plasma, Tissue Homogenates;Synonym:C C motif chemokine 24 ELISA Kit; C-C motif chemokine 24 ELISA Kit; CCL24 ELISA Kit; CCL24_HUMAN ELISA Kit; Chemokine CC Motif Ligand 24 ELISA Kit; CK beta 6 ELISA Kit; CK-beta-6 ELISA Kit; Ckb6 ELISA Kit; Eosinophil chemotactic protein 2 ELISA Kit; Eotaxin-2 ELISA Kit; MPIF 2 ELISA Kit; MPIF-2 ELISA Kit; MPIF2 ELISA Kit; Myeloid progenitor inhibitory factor 2 ELISA Kit; SCYA24 ELISA Kit; Small inducible cytokine A24 ELISA Kit; Small inducible cytokine subfamily A (Cys-Cys) member 24 ELISA Kit; Small-inducible cytokine A24 ELISA Kit;Description:This human CCL24 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of human CCL24 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the CCL24 levels in the sample and is measured at 450 nm through a microplate reader. CCL24, also known as eotaxin2, mainly chemoattracts eosinophils. It can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 promotes cell trafficking and regulates inflammatory and fibrotic activities mainly through the CCR3. CCL24 induces chemotaxis and activation of CCR3-expressing cells, including immune cells and fibroblasts. A study found that CCL24 stimulated human lung fibroblast proliferation and collagen synthesis and was associated with the progression of idiopathic pulmonary fibrosis. Suppressing the expression of CCL24 can reduce airway inflammation. Macrophages can also selectively induce the production of CCL24.;Species Reactivity:Human;Usage:For Research Use Only;Detection Principle:Sandwich ELISA;Detection Range:78.125 pg/mL-5000 pg/mL;Sensitivity:67.660 pg/mL;