Cat#:EIA-332C;Product Name:Mouse Chemokine (C-C motif) Ligand 11, Ccl11 ELISA Kit;Size:10 plates;Intended use:RUO;Synonym:Ccl11; chemokine (C-C motif) ligand 11; Scya11; SCYA11; eotaxin; eotaxin-1; MGC22554; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); small inducible cytokine A11; C-C motif chemokine 11; Eosinophil chemotactic protein;Background:Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin-1. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.[5] The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.;Species Reactivity:Mouse;Application:Quantitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Sandwich ELISA;