Cat#:EIA-468C;Product Name:Human Interleukin 6 Receptor, IL6R ELISA Kit;Size:5 plates;Intended use:RUO;Synonym:IL6R; CD126; IL-6R-1; IL6R-alpha; IL-6R-alpha; IL6RA; MGC104991; OTTHUMP00000034320; gp80; CD126 antigen; IL-6R 1; Interleukin-6 receptor alpha chain precursor; B cell stimulatory factor-2; Membrane glycoprotein 80; interleukin 6 receptor; interleukin 6 receptor alpha subunit;Background:This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.;Species Reactivity:Human;Application:Quantitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Sandwich ELISA;