Cat#:EIA-399C;Product Name:Human TNFSF11 ELISA Kit;Size:96 T;Sample:EDTA PLASMA, HEPARIN PLASMA, SERUM OR CELL CULTURE;Intended use:N/A;Synonym:TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; TNF-related activation-induced cytokine; OPGL; OPTB2; TRANCE; OTTHUMP00000178585; ODF; hRANKL2; RANKL; receptor activator of nuclear factor kappa B ligand; CD254; sOdf; Osteoclast differentiation factor; tumor necrosis factor ligand superfamily member 11; Osteoprotegerin ligand; CD254 antigen; Receptor activator of nuclear factor kappa-B ligand; OTTHUMP00000018328;Background:sRANKL, soluble receptor activator of nuclear factor (NF)-kB ligand (also: Osteoprotegerin ligand, OPGL) a member of the tumor necrosis factor (TNF) family, is the main stimulatory factor for the formation of mature osteoclasts and is essential for their survival. RANKL is produced by osteblastic lineage cells and activated T lymphocytes. It activates its specific receptor RANK that is located on osteoclasts and dendritic cells. The effects are counteracted by OPG (compare BI-20402 OPG ELISA), which is secreted by various tissues and acts as an endogeneous soluble receptor antagonist.;Species Reactivity:Human;Application:Quantitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Sandwich ELISA;