Cat#:EIA-231C;Product Name:Parainfluenza 1 / 2 / 3 IgG ELISA Kit;Size:96 T;Sample:serum and plasma;Intended use:in-vitro diagnostic;Synonym:HPIVs; Parainfluenza 1/2/3 virus; HPIV3; Parainfluenza 3 virus; PIV3; HPIV 1; hPIV1; Human parainfluenza 1 virus; Human parainfluenza virus type; Parainfluenza 1 virus; Parainfluenza; Parainfluenza Type 1; Parainfluenza1;Background:The infection with parainfluenza viruses is air-borne from man-to-man. Various species of animals may serve as virus reservoir. Parainfluenza viruses are endemically spread worldwide. The seroprevalence of parainfluenza in infants in their first year of life is 50%. Typical for parainfluenza viruses are frequent reinfections, this applies particularly to parainfluenza 3 viruses. Incubation time is 2-6 days. The parainfluenza viruses are a subgroup of the paramyxoviruses. They are of the same size of approximately 150 - 300 nm. They are ether-sensitive, agglutinate human or chicken erythrocytes and have a receptor-destructive enzyme, as known from influenza viruses. They can be cultivated best in primary monkey cell cultures or in human epithel cell cultures, however, less successful in embryonized chicken eggs. lt is differentiated between parainfluenza 1, 2, 3 and 4. Together with the respiratory syncytial viruses (RS viruses), the pathogens belong to the major viral pathogens of diseases of the respiratory tract, accompanied by severe clinical symptoms. In adults, parainfluenza virus causes a feverish rhinitis and laryngitis. First signs are sudden headaches, pain in muscles and joints, followed by fever of 38°-39°C. If the lower respiratory tract is involved, additionally trachyphonea and dry cough develops as a sign of tracheobronchitis. Parainfluenza 1 causes severe pneumonias in newborns, manifested by high fever, cyanosis, dyspnoea and bloody purulent sputum. Sometimes. meningitis symptoms occur at the same time. Parainfluenza 2 very often causes an acute laryngotracheobronchitis with pseudocroup in infants and children. First signs of the infection are catarrhal symptoms, followed by trachyphoena, dry barking cough and inspiratory stridor. Parainfluenza 3 viruses are considered the major pathogens of pneumonia and bronchiolitis. While types 1, 2 and 3 are distributed worldwide, parainfluenza type 4 appears only in the USA. Infections 1 and 3 occur all the year, while parainfluenza 2 and 4 viruses appear only sporadically.;Species Reactivity:virus;Application:quantitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:I-ELISA;