Cat#:EIA-218C;Product Name:Poliomyelitis; Poliomyelitis vieus; Polio;Size:96 T;Sample:serum and plasma;Intended use:in-vitro diagnostic;Synonym:Poliomyelitis; Poliomyelitis Virus; Polio;Background:Poliomyelitis is an infection caused by enterovirus, which occurs epidemically world-wide, and which often leads to paralysis and death. Three types of human-pathogenic poliomyelitis viruses are actually known: Type 1 (Brunhilde): often with severe symptoms Type 2 (Lansing): with milder symptoms Type 3 (Leon): rare, but with severe symptoms Polioviruses mainly proliferate in the lymph nodes of the intestine, and are excreted via feces. The throat can also be infected, and the viruses then leave the body orally. After the infection, the viruses are distributed via monocytes into other lymph nodes, where they multiplicate. In a second viremic phase they settle in the whole organism, amongst others in the central nervous system. In more than 90% of the infections the patient does not suffer any subjective symptoms. In the remaining other cases there appear: unspecific illness with slight fever, head and throat irritations, diarrhoea, nausea, and vomiting. Very rarely the classical paralysis with affliction of muscles and cerebral nerves is seen. The reconvalescent phase can last up to two years, frequently there stay long-lasting damages. There exists no treatment of the disease, only symptomatic therapy with acetylsalicylic acid and gymnastics is possible. In many countries of the Asiatic area poliomyelitis is still endemic, but WHO has started ambitious projects to eradicate the disease. In Europe there exist cases which are imported by tourists, sometimes with lethal outcome.;Species Reactivity:Virus;Application:quantitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:I-ELISA;