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Antibody / Primary Antibody / Polyclonal Antibody
Antibody  /  Primary Antibody  /  Polyclonal Antibody
 Polyclonal antibodies (PAbs) play a crucial role in various biomedical and diagnostic applications owing to their ability to recognize multiple epitopes on an antigen. This essay will delve into the general introduction, production, and utilization of polyclonal antibodies, highlighting their significance in scientific research and medical diagnostics.
 
Production of Polyclonal Antibodies
Polyclonal antibodies are a heterogeneous mixture of antibodies secreted by different B cell lineages in response to a specific antigen. Each antibody within the polyclonal mixture identifies a distinct epitope on the antigen, providing a diverse and comprehensive immune response.
 
The production of polyclonal antibodies typically involves immunizing an animal, such as rabbits, goats, or sheep, with the desired antigen. These animals are chosen for their ease of handling and ability to produce significant quantities of serum. Upon immunization, B lymphocytes recognize the antigen and produce immunoglobulin G (IgG) specific to it. The serum containing polyclonal IgG is then collected and purified, often through techniques like ammonium sulfate precipitation.
 
One of the key advantages of polyclonal antibody production is its speed and cost-effectiveness compared to monoclonal antibody production. Additionally, polyclonal antibodies can be highly specific and yield high concentrations from relatively small amounts of serum. However, one limitation is the heterogeneous nature of polyclonal antiserum, which can make it challenging to reproduce consistent results across different batches.
 
What polyconal antibody can be used in?
In terms of utilization, polyclonal antibodies find widespread application in immunosensor-based assays for pathogen detection. Various animal sources have been successfully employed to generate polyclonal antibodies targeting specific molecules. Despite their usefulness in recognizing a broad range of epitopes, polyclonal antibodies may have limited applicability in assays requiring high specificity.
 
Furthermore, polyclonal antibodies are utilized in various research fields, including immunohistochemistry, flow cytometry, and Western blotting. Their ability to recognize multiple epitopes makes them valuable tools for studying complex biological systems and identifying specific proteins within cells and tissues.
 
We offer a diverse selection of polyclonal antibodies for your needs. Simply utilize our filters and search box to locate the specific antibody you require. If you have an interest in antibodies not currently listed, please don't hesitate to reach out to us at [email protected]. Our team of antibody experts is here to assist you.
 


  • CAT. #
  • PRODUCT NAME
  • Host Species
  • PRICE
Cat.#: ADC-01134A Product Name: Rabbit anti-Human TBK1 Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01133A Product Name: Rabbit anti-Human TBK1 Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01132A Product Name: Rabbit anti-Human TBK1 Polyclonal Antibody, Biotin conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01131A Product Name: Rabbit anti-Human FEM1B Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01130A Product Name: Rabbit anti-Human FEM1B Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01129A Product Name: Rabbit anti-Human FEM1B Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01127A Product Name: Rabbit anti-Human SLC39A10 Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01123A Product Name: Rabbit anti-Human TENM1 Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01122A Product Name: Rabbit anti-Human TENM1 Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01121A Product Name: Rabbit anti-Human TENM1 Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01119A Product Name: Rabbit anti-Human NENF Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01118A Product Name: Rabbit anti-Human NENF Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01117A Product Name: Rabbit anti-Human NENF Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01116A Product Name: Rabbit anti-Human NENF Polyclonal Antibody, Biotin conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01115A Product Name: Rabbit anti-Human IVNS1ABP Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01111A Product Name: Rabbit anti-Human ARL2BP Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01110A Product Name: Rabbit anti-Human ARL2BP Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01109A Product Name: Rabbit anti-Human ARL2BP Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01107A Product Name: Rabbit anti-Human ATP6V1D Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01106A Product Name: Rabbit anti-Human ATP6V1D Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01099A Product Name: Rabbit anti-Mus musculus (Mouse) Slfn9 Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01037A Product Name: Rabbit anti-Human TTYH2 Polyclonal Antibody
Source (Host): Species: Rabbit
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Cat.#: ADC-01036A Product Name: Rabbit anti-Human TTYH2 Polyclonal Antibody, HRP conjugated
Source (Host): Species: Rabbit
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Cat.#: ADC-01035A Product Name: Rabbit anti-Human TTYH2 Polyclonal Antibody, FITC conjugated
Source (Host): Species: Rabbit
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