Cat#:PDE9A-RP01EH;Product Name:Active Recombinant Human PDE9A Protein(GST Tag);Synonym:PDE9A, phosphodiesterase 9A, HSPDE9A2, FLJ90181;Background:PDE9A, the full name is phosphodiesterase 9A. Gene ID: 5152. The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008];Description:Recombinant human PDE9A protein was expressed by baculovirus in Sf9 insect cells. The PDE9A human was fused with a GST tag at N-terminal. ;Source:Sf9 insect cells;AA Sequence:Full Length;Molecular Characterization:86 kDa ;Purity:The purity of PDE9A protein is greater than 95% as determined by densitometry.;Bioactivity:The activity of PDE9A protein was determined to be 53 nmol/min/mg ;Formulation:Liquid Solution;Stability:Recombinant human PDE9A proteins are stable for up to 1 year from date of receipt at -70℃;Host Species:Human;Application:PDE Assay;Concentration:0.1ug/ul;Storage:The recombiant human PDE9A protein is shipped using dry ice. Store recombinant human KAT2A enzyme at –70 degree. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Please avoid repeated freeze/thaw cycles.;Usage:For Lab Research Use Only;Supplied in:50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. ;References:Identification and characterization of a new human type 9 cGMP-specific phosphodiesterase splice variant (PDE9A5). Differential tissue distribution and subcellular localization of PDE9A variants. Wang P, et al. Gene, 2003 Sep 18. PMID 14527714;