Cat#:LTA-RP01H;Product Name:Recombinant Human TNFB / TNFSF1 / LTA Protein;Synonym:LT; TNFB; TNFSF1; TNLG1E;Background:Gene ID: 4049. LTA, full name is lymphotoxin alpha, also known as LT,TNFB,TNFSF1,TNLG1E. The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.;Description:Recombinant Human LTA Protein produced in E.coli was fused with His Tag. Recombinant human LTA protein was purified with an initial Met at the N-terminus.;Source:E. coli;Predicted N Terminal:Met;AA Sequence:Leu 35-Leu 205;Molecular Characterization:The recombinant human TNFB protein contains 172aa and predicts a molecular mass of 18.8 kDa as estimated in SDS-PAGE under reducing conditions.;Purity:Greater than 97 % as determined by SDS-PAGE;Bioactivity:Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D.The ED50 for this effect is typically 0.01-0.1 ng/mL.;Formulation:Recombinant human TNFB protein was lyophilized from sterile 50mM Tris, pH 8.0;Stability:Recombinant humman LTA Proteins are stable for up to 1 year from date of receipt at -70℃;Host Species:Human;Storage: Avoid repeated freeze-thaw cycles. Store recombinant human LTA protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage.;Usage:For Research Use Only!;References:LTA + 252A > G polymorphism is associated with risk of nasal NK/T-cell lymphoma in a Chinese population: a case-control study. Cheng S, et al. BMC Cancer, 2015 Jun 25.;