Cat#:BTLA-1009HRP;Product Name:Recombinant Human BTLA / CD272 Protein(Fc Tag);Synonym:BTLA1; CD272;Background:Gene ID: 151888. BTLA, full name is B and T lymphocyte associated, also known as BTLA1 and CD272. This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.;Description:Recombinant human BTLA protein was produced in human cells. A DNA sequence encoding the human BTLA protein was expressed with the Fc Tag at the C-terminus. Recombinant human CD272 protein was purified using our unique purification methods.;Source:Human Cells;Predicted N Terminal:Met;AA Sequence:Met1-Thr134;Molecular Characterization:The human BTLA recombinant protein comprises 372aa and has a predicted molecular weight of 42.2 kDa.;Purity:Greater than 90% as determined by SDS-PAGE;Endotoxin:< 1.0 EU per μg of the human BTLA protein as determined by the LAL method;Bioactivity:The EC50 is 6-70ng/mL.;Formulation:The recombinant human BTLA protein was lyophilized from sterile PBS, pH 7.4.;Stability:Human BTLA protein is stable for up to 1 year from date of receipt at -70℃;Host Species:Human ;Storage:Avoid repeated freeze-thaw cycles. Store the human BTLA protein under sterile conditions at -20℃ to -80℃. It is recommended that the CD272 protein be aliquoted for optimal storage. ;References:BTLA-expressing CD11c antigen presenting cells in patients with active tuberculosis exhibit low capacity to stimulate T cell proliferation. Wang WD, et al. Cell Immunol, 2017 Jan. ;