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Large scale protein production


With the fast growth of the protein drug market and recent advances in proteomics, the demand for large quantities of highly purified and bioactive recombinant proteins has been increasing. Large-scale recombinant protein production is becoming increasingly important for pharmaceutical development, industrial processes, and other applications.
 
Advanced Biomart is fully equipped to meet this demand for large-scale protein production and purification service under GLP. Experienced and professional technical team will complete your project at well-established facility by using our proprietary protein expression technology. Our versatile and reliable protein expression platforms, include fermentors, wave mixers, and bioreactors, which accommodate different scales of protein production, from milligrams to gram scale per batch. Our process development and optimization service can significantly improve the recovery rate and the bioactivity of your recombinant proteins.
 

 
 Advantages:
 
 Multi expression systems for your selection: bacterial, baculovirus-insect cells, yeast, and mammalian cells
 
 One-stop service
 
 Ability to characterize a protein with mass spectrometry, cellular behavior, immunology, and enzyme activity
 
 Time saving & Cost effective


  Capabilities Specifications:


Bacteria
• Transformed bacterial culture for large-scale fermentation, up to 2,000L.
• Provides homogeneous recombinant proteins, over 98% pure, for crystallization, and partially purified recombinant proteins, over 70% pure.
• Provides large quantities of protein, up to several grams
Fermentor
Yeast
• Yeast culture up to 2,000L for large-scale fermentation.
• Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
• Provides partially purified recombinant proteins, over 70% pure.
• Provides large quantities of protein, up to grams.
Baculovirus-Insect Cells
• High titer recombinant baculovirus stock carrying the customer's gene.
• Provides homogeneous recombinant proteins, over 98% pure, for crystallization.
• Provides partially purified recombinant proteins, over 70% pure.
• Provides a large scale protein production option, up to few hundreds of mg, using insect cells and a wave mixer system.
Wave Mixer
Mammalian Cells
• Provides one single system for the production of final homogeneous recombinant proteins; from gene synthesis to expression; for orders of up to 100mg.
• Permits transient expression of customers' proteins of interest, up to 10mg in 10 days.
• Provides conditioned media and cell pellets from stable cell lines, up to 500L, using a wave mixer system

For quotation requests and other detailed information of our Large scale protein production service, Welcome to contact us or send an email to info@advbiomart.com. 
 

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