Cat#:ABRP-0003;Product Name:Recombinant Human PCNA Protein(HIS Tag);Synonym:MGC8367;Background:Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling and epigenetics.;Description:Recombinant full-length human PCNA was produced in E. coli cells using an N-terminal His tag.;Source:E.coli;AA Sequence:Full Length;Molecular Characterization:~37kDa;Purity:For specific information on a given lot, see related product datasheet.;Endotoxin:<1.0 EU per μg of the recombinant protein as determined by the LAL method;Bioactivity:Please contact us for detailed information;Formulation:Liquid Solution;Stability:Recombinant Human PCNA Protein is stable up to 1 year from date of receipt at -70℃;Host Species:Human;Application:WB; Immunogen;Storage:Store Recombinant Human PCNA Protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.;Usage:For Lab Resarch Use Only!;Supplied in:50mMsodiumphosphate,pH7.0,300mMNaCl,150mMimidazole,0.1mMPMSF,0.25mMDTT,25%glycerol.;
Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling and epigenetics.
Description:
Recombinant full-length human PCNA was produced in E. coli cells using an N-terminal His tag.
Source:
E.coli
AA Sequence:
Full Length
Molecular Characterization:
~37kDa
Purity:
For specific information on a given lot, see related product datasheet.
Endotoxin:
<1.0 EU per μg of the recombinant protein as determined by the LAL method
Bioactivity:
Please contact us for detailed information
Formulation:
Liquid Solution
Stability:
Recombinant Human PCNA Protein is stable up to 1 year from date of receipt at -70℃
Store Recombinant Human PCNA Protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.