Cat#:PA-4144F;Product Name:Rabbit Anti-Alpha-1-Fetoprotein (AFP) Antibody;Synonym:AFP; alpha-fetoprotein; FETA; HPAFP; alpha-fetoprotein; OTTHUMP00000160480; OTTHUMP00000220440; alpha-fetoglobulin; alpha-1-fetoprotein;Background:AFP is a 70 kDa glycoprotein containing 590 amino acid residues. Cells of the embryonic yolk sac, fetal liver, and fetal intestinal tract synthesize this glycoprotein. AFP is a very useful marker for the detection of numerous developmental defects and various pathologies, whether cancerous or not. Expression of AFP has been demonstrated in about 44% of hepatocellular carcinomas, and in gonadal and extragonadal germ cells tumours, including yolk sac tumours. AFP has not been detected in normal adult tissue by immunostaining. However, traces of AFP are found in normal adult sera and in greater concentrations in maternal and foetal sera and amniotic fluid.;Description:Rabbit Anti-Alpha-1-Fetoprotein (AFP) Polyclonal Antibody;Formulation:Liquid Solution;Host Species:Rabbit;Species Reactivity:Human;Isotype:N/A;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;