Cat#:PA-4074F;Product Name:Mouse Anti-Human AMACR Antibody;Synonym:AMACR; alpha-methylacyl-CoA racemase; RM; RACE; CBAS4; alpha-methylacyl-CoA racemase; OTTHUMP00000115916; OTTHUMP00000115917; OTTHUMP00000219978; OTTHUMP00000219979; OTTHUMP00000219980; 2-methylacyl-CoA racemase;Background:This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.;Description:Mouse Anti-Human AMACR Monoclonal Antibody;Formulation:Liquid Solution;Host Species:Mouse;Species Reactivity:Human;Clone#:13I5;Isotype:N/A;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;