Cat#:RP-1552M;Product Name:Recombinant Mouse TIM4 / TIMD4 Protein (His Tag);Synonym:TIM-4; Tim4; B430010N18Rik;Background:Gene ID: 276891. Timd4, the full name is T-cell immunoglobulin and mucin domain-containing protein 4, also known as TIM-4, Tim4, B430010N18Rik. A type I transmembrane protein called TIM4 (T-cell immunoglobulin- and mucin-domain-containing molecule; also known as TIMD4), which belongs to the immunoglobulin superfamily and TIM family. Low expression of Timd4 is associated with lymphotoxin deficiency. The interaction of TIM1/TIM4 played a critical role in sustaining the polarization status of Th2 cells in allergic rhinitis (AR) patients.;Description:Mouse TIM-4 protein was produced in human cells. A DNA sequence encoding the extracellular domain of mouse TIMD4 precursor was expressed, fused with a His tag at C-terminal. The TIMD4 mouse was purified using our unique purification techniques.;Source:Human Cells;Predicted N Terminal:Ala23;AA Sequence:Met1-Thr279;Molecular Characterization:The secreted recombinant TIMD4 mouse has a predicted molecular weight of 29.3 kDa comprising 268aa. As a result of diiferent glycosylation, the apparent molecular weight of recombinant mouse TIM-4 is approximately 60-70 kDa in SDS-PAGE under reducing conditions.;Purity:Greater than 94% as determined by SDS-PAGE;Endotoxin:< 1.0 EU per ug of the mouse TIMD4 protein as determined by the LAL method;Bioactivity:Please contact us for detailed information;Formulation:Recombinant mouse TIMD4 protein was lyophilized from sterile PBS, pH 7.4;Stability:Recombinant mouse TIM-4 Protein is stable for up to 1 year from date of receipt at -70℃;Host Species:Human;Storage:Avoid repeated freeze-thaw cycles. Store mouse TIM-4 protein under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage.;Usage:For Research Use Only!;References:TIM-4 promotes the growth of non-small-cell lung cancer in a RGD motif-dependent manner. Zhang Q, et al. Br J Cancer, 2015 Nov 17. ;