Cat#: | RP-6003H |
Product Name: | Recombinant Human CCL17 / TARC Protein |
Synonym: | C-C motif chemokine 17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CC chemokine TARC, ABCD-2, CCL17, CCL-17, SCYA17, TARC, A-152E5.3, MGC138271, MGC138273. |
Description: | Recombinant human CCL17 Protein expressed in E.coli is a single,non-glycosylated, polypeptide chain containing 71 amino acids and having a molecular mass of 8 kDa. The recombinant human TARC protein is purified using our unique chromatographic techniques. |
Source: | E.coli |
AA Sequence: | ARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRD AIVFVTVQGRAICSDPNNK RVKNAVKYLQSLERS. |
Purity: | Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Bioactivity: | The recombinant human CCL17 protein was determined by its ability to chemoattract human T-Lymphocytes using a concentration range of 1.0-10.0 ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg. |
Formulation: | The recombinant human CCL17 protein was lyophilized from a concentrated (0.5mg/ml) solution containing 20mM PBS & 150mM NaCl pH-7.4. |
Stability: | Recombinant Human CCL17 Proteins are stable for up to 1 year from date of receipt at -70℃ |
Reconstitution: | It is recommended to reconstitute the lyophilized human CCL17 protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Storage: | Lyophilized recombinant human CCL17 / TARC protein although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution recombinant human TARC protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
References: | Tumor-associated macrophage or chemokine ligand CCL17 positively regulates the tumorigenesis of hepatocellular carcinoma. Zhu F, et al. Med Oncol, 2016 Feb. PMID 26781124 |