Cat#:EIA-778C;Product Name:Anti HBcAg ELISA Kit;Size:96 T;Sample:human serum or plasma;Intended use:IVD;Synonym:hepatitis B core; HBc; Group VII (dsDNA-RT); Unassigned; Hepadnaviridae; Orthohepadnavirus; Hepatitis B virus;Background:Hepatitis B is a disease produced by a viral infection during which many serological markers appear. One of these markers is the anti-HBc. The hepatitis B core antigen (HBcAg) is an internal component of hepatitis B virus which is antigenically distinct from hepatitis B surface antigen (HBsAg). HBcAg/anti-HBc antigen-antibody system was described by Almeida et al. in 1971. Antibodies to HBcAg (anti-HBc) are the first to be developed in the course of an acute hepatitis B infection and may persist for life. Anti-HBc can usually be detected in the blood just after the detection of HBsAg and before the onset of clinically apparent hepatitis. In acute hepatitis B with recovery, anti-HBc is the only serological marker of infection in the period between HBsAg clearance and the appearance of anti-HBs. Blood donations taken at this stage may be infectious and it has been suggested that screening for anti-HBc as well as for HBsAg might further reduce the incidence of post transfusion hepatitis B. On the other hand, the screening for anti-HBc should also be performed on any individual before the administration of hepatitis B vaccine to know the immune status in order to vaccinate only the anti-HBc negative individuals. Furthermore several reports have shown a correlation between the presence of anti-HBc in donated blood and the incidence of transfusion associated non-A non-B hepatitis (NANBH or hepatitis C). With the implementation of anti-HBc screening of blood donors, many of these cases could be prevented.;Species Reactivity:Virus;Application:qualitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Competitive ELISA;