Cat#:RP-282AC;Product Name:Recombinant Rhesus macaque EGFR Protein(Fc Tag);Synonym:EGFR,ERBB,ERBB1,HER1,PIG61,mENA;Background:Gene ID: 613027. EGFR, the full name is epidermal growth factor receptor [Macaca mulatta (Rhesus monkey)]. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer.;Description:Rhesus macaque EGF R with Fc Tag is produced in HEK293 cells. It contains AA Leu 25 - Ser 645.;Source:HEK293;Predicted N Terminal:Leu 25;Molecular Characterization:Recombinant Rhesus macaque EGFR Protein has a calculated MW of 95.3 kDa. The recombinant protein migrates as 130-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.;Purity:Greater than 95% as determined by SDS-PAGE.;Endotoxin:< 1.0 EU per μg of recombinant rhesus macaque EGFR protein by the LAL method.;Formulation:Recombinant rhesus macaque EGFR protein was lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5.;Stability:Recombinant rhesus macaque EGFR protein was stable up to 1 year from date of receipt at -70℃;Host Species:Rhesus macaque ;Storage:Store recombinant rhesus macaque EGFR protein under sterile conditions at -20℃ to -80℃. It is recommended that the recombinant protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;References:Fukihara J, etal. Clinical predictors of response to EGFR tyrosine kinase inhibitors in patients with EGFR-mutant non-small cell lung cancer.Oncology. 2014;86(2):86-93. doi: 10.1159/000357129. Epub 2014 Jan 18. ;