Cat#: | PA-130F |
Product Name: | Rabbit Anti-Human UNG (N-terminal) Antibody |
Synonym: | UNG; uracil-DNA glycosylase; DGU; UDG; UNG1; UNG2; HIGM4; UNG15; DKFZp781L1145; uracil-DNA glycosylase |
Gene Introduction: | Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. The human gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. |
Description: | Rabbit Anti-Human UNG (N-terminal) Polyclonal Antibody |
Formulation: | Liquid Solution |
Host Species: | Rabbit |
Species Reactivity: | Human |
Application: | WB |
Usage: | For Lab Research Use Only |
Storage: | Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles |