Cat#: | PA-106F |
Product Name: | Mouse Anti-Human VEGFA Antibody |
Synonym: | VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; VEGF-A; MGC70609; vascular permeability factor; vascular endothelial growth factor isoform VEGF165; vascular endothelial growth factor; OTTHUMP0000001648; OTTHUMP00000016488; OTTHUMP00000165985; OTTHUMP00000165986; OTTHUMP00000165987; OTTHUMP00000224107; OTTHUMP00000224108; OTTHUMP00000224109; OTTHUMP00000224153; OTTHUMP00000224154; OTTHUMP00000224423; OTTHUMP00000224424; OTTHUMP00000224425; OTTHUMP00000224426; OTTHUMP00000224427; OTTHUMP00000224428; OTTHUMP00000224429; OTTHUMP00000224430 |
Gene Introduction: | The human VEGFA gene, located on chromosome 6p21.3, contains 8 exons separated by 7 introns. Alternative exon splicing results in generation of 6 different isoforms, VEGF-121, VEGF-145, VEGF-165, VEGF-183, VEGF-189, and VEGF-206, which are named according to the number of amino acids in the peptide chain. Native VEGF protein is a heparin-binding homodimeric glycoprotein of 45 kDa. VEGF-121 is a weakly acidic polypeptide that fails to bind to heparin, while VEGF-165 and VEGF-189 are more basic and bind heparin with increasingly greater affinities. Of these 3 isoforms, VEGF-165 is the predominant molecular form produced in normal cells and tissues. The other isoforms, VEGF-121 and VEGF-189, are detected in the majority of cells and tissues that express the VEGF gene. |
Description: | Mouse Anti-Human VEGFA Monoclonal Antibody |
Formulation: | Liquid Solution |
Host Species: | Mouse |
Species Reactivity: | Human |
Clone#: | VH2 |
Isotype: | IgG1, kappa |
Application: | IHC |
Usage: | For Lab Research Use Only |
Storage: | Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles |