Cat#: | FPA-21849P |
Product Name: | Rabbit Anti-IRG1 Polyclonal Antibody |
Gene Introduction: | IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions. It is also highly expressed in the pregnant uterus during implantation. IRG1 is a cis-aconitate decarboxylase that produces itaconic acid by decarboxylating cis-aconic acid, an intermediate of the tricarboxylic acid cycle. Itaconic acid is an endogenous inhibitor of succinate dehydrogenase, linking macrophage metabolic rewiring and regulation of inflammation. |
Description: | Rabbit polyclonal antibody to IRG1. The rabbit anti IRG1 antibody was purified using our unique Immunogen affinity techniques |
Source: | Rabbit |
Purity: | Immunogen affinity purified |
Formulation: | Liquid |
Host Species: | Rabbit |
Immunogen: | Synthetic peptide according to IRG1 |
Species Reactivity: | Human |
Isotype: | IgG |
Application: | WB: 1/1000 - 1/3000. Predicted molecular weight: 53 kDa. |
Positive control: | WB: LoVo whole cell lysate. |
Concentration: | 1 mg/ml |
Storage Buffer: | pH: 7.40 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol, PBS, 0.87% Sodium chloride |
Storage: | Store rabbit IRG1 antibody at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Please avoid freeze / thaw cycle. |