Cat#:RP-275AC;Product Name:Recombinant Human VEGFR3 / FLT4 Protein(Fc Tag);Synonym:Flt-4,FLT4,LMPH1A,PCLFLT41,VEGFR3,VEGFR-3,FLT-4,FLT-41,FLT41,PCL;Background:Gene ID: 2324. FLT4, the full name is fms related tyrosine kinase 4 [ Homo sapiens (human) ]. Also known as: PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008];Description:Human VEGF R3 with Fc Tag is produced in HEK293 cells. It contains AA Tyr 25 - Ile 776.;Source:HEK293;Predicted N Terminal:Tyr 25;AA Sequence:Tyr 25 to Ile 776;Molecular Characterization:Recombinant Human VEGFR3 / FLT4 Protein has a calculated MW of 111.2 kDa. As a result of glycosylation, The recombinant protein migrates as 140-160 kDa under reducing (R) condition, and 280-320 kDa under non-reducing (NR) condition (SDS-PAGE).;Purity:Greater than 95% as determined by SDS-PAGE.;Endotoxin:< 1.0 EU per μg of recombinant human VEGFR3 / FLT4 protein by the LAL method.;Formulation:Recombinant human VEGFR3 / FLT4 protein was lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5.;Stability:Recombinant human VEGFR3 / FLT4 protein was stable up to 1 year from date of receipt at -70℃;Host Species:Human;Storage:Store recombinant human VEGFR3 / FLT4 protein under sterile conditions at -20℃ to -80℃. It is recommended that the recombinant protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.;Usage:For Lab Research Use Only;References:A NOVEL FLT4 GENE MUTATION AND MR LYMPHANGIOGRAPHY IN A CHINESE FAMILY WITH MILROY DISEASE. Liu NF, et al. Lymphology, 2015 Jun. PMID 26714373;