Cat#: | CCL8-001HP |
Product Name: | Recombinant Human CCL8 / MCP-2 Protein (SUMO Tag) |
Synonym: | CCL8, Monocyte chemotactic protein 2, MCP-2, Monocyte chemoattractant protein 2, HC14, chemokine (C-C motif) ligand 8, MCP2, Small inducible cytokine A8 |
Description: | Recombinant human CCL8 protein produced in E. coli was fused with the SUMO tag at the N-terminus. The recombinant human MCP-2 protein is purified by our unique chromatographic techniques. |
Source: | E. coli |
Predicted N Terminal: | Met |
Molecular Characterization: | The recombinant human CCL8 protein consisting of 187 amino acids and has a calculated molecular mass of 21.7 kDa. The apparent molecular mass of the protein is approximately 30 kDa in SDS-PAGE under reducing conditions. |
Purity: | Greater than 90 % as determined by SDS-PAGE |
Formulation: | Recombinant human CCL8 protein was lyophilized from sterile PBS, pH 7.4 |
Stability: | Recombinant human CCL8 proteins are stable for up to 1 year from date of receipt at -70℃ |
Storage: | Store recombinant human CCL8 protein under sterile conditions at -20℃ to -80℃. It is recommended that the human MCP-2 protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
References: | Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effects. Struyf S, et al. Eur J Immunol, 2009 Mar. PMID 19224633 |