Cat#:RP-1794H;Product Name:Recombinant Human Epidermal Growth Factor / EGF Protein;Synonym:EGF, Urogastrone, URG;Background:This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016];Description:Recombinant human EGF protein expressed in E.coli has the molecular weight at 6.2kDa. The egf recombinant protein is purified using our unique techniques.;Source:E.coli;Molecular Characterization:Approximately 6.2 kDa, a single non-glycosylated polypeptide chain containing 53 amino acids.;Purity:Greater than 98% as determined by SDS-PAGE and HPLC analyses;Endotoxin:<1.0 EU per μg human EGF protein as determined by the LAL method.;Bioactivity:> 1.0 × 107 IU/mg;Formulation:EGF recombinant human protein was lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.2.;Stability:Recombinant EGF Proteins are stable for up to 1 year from date of receipt at -70℃;Reconstitution:Please see related COA for specific instructions.;Host Species:Human ;Storage:Avoid repeated freeze-thaw cycles. In lyophilized state for 1 year (4-8℃); Upon reconstitution under sterile conditions for 2 weeks (4-8℃) or 3 months (-20℃ to -80℃).;References:1.Epidermal growth factor promotes proliferation and maintains multipotency of continuous cultured adipose stem cells via activating STAT signal pathway in vitro. Ai G, et al. Medicine (Baltimore), 2017 Jul. PMID 28746211; 2.Salivary epidermal growth factor correlates with hospitalization length in ;