Cat#:EIA-191C;Product Name:Rat IgM ELISA Kit;Size:96T;Sample:serum or plasma;Intended use:RUO;Synonym:IgM; Immunoglobulin M; Constant region of heavy chain of IgM; Hepatitis B virus receptor binding protein; Ig mu chain C region; IGHM; Immunoglobulin mu chain; Imunoglobulin heavy chain; VH;Background:There are five classes of mammalian immunoglobulins: IgA, IgD, IgE, IgG, and IgA. The rat IgG antibody has multiple functions including opsonization, complement function, and antibody-dependent cell mediated cytotoxicity. Rat IgG has been further categorized into subclasses: IgG1, IgG2a, IgG2b, and IgG2c. Functionally, Rat IgG1 and IgG2a have been shown to bind complement. This is in contrast to mice where only IgG2a binds complement. In rats, as with other mammals, IgA functions primarily in mucosal immunity. Rat IgM functions primarily as a naïve B-cell receptor and in complement functions. Concentrations of Rat IgM in serum are typically shown to be in the range of 0.6 to 1.0 mg/ml.;Species Reactivity:Rat;Application:quantitate;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Sandwich ELISA;
IgM; Immunoglobulin M; Constant region of heavy chain of IgM; Hepatitis B virus receptor binding protein; Ig mu chain C region; IGHM; Immunoglobulin mu chain; Imunoglobulin heavy chain; VH
Size:
96T
Sample:
serum or plasma
Intended use:
RUO
Gene Introduction:
There are five classes of mammalian immunoglobulins: IgA, IgD, IgE, IgG, and IgA. The rat IgG antibody has multiple functions including opsonization, complement function, and antibody-dependent cell mediated cytotoxicity. Rat IgG has been further categorized into subclasses: IgG1, IgG2a, IgG2b, and IgG2c. Functionally, Rat IgG1 and IgG2a have been shown to bind complement. This is in contrast to mice where only IgG2a binds complement. In rats, as with other mammals, IgA functions primarily in mucosal immunity. Rat IgM functions primarily as a naïve B-cell receptor and in complement functions. Concentrations of Rat IgM in serum are typically shown to be in the range of 0.6 to 1.0 mg/ml.
Species Reactivity:
Rat
Application:
quantitate
Usage:
For Lab Research Use Only
Detection Principle:
Sandwich ELISA
Storage:
Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.