Cat#:EIA-126C;Product Name:Treponema Pallidum IgG and IgM ELISA Kit;Size:96 T;Sample:human serum or plasma;Intended use:IVD;Synonym:T. pallidum; Treponema pallidum; Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema;Background:Syphilis is a disease caused by infection with the spirochete bacterium Treponema pallidum, ordinarily transmitted by sexual contact. However, it can also be transmitted congenitally by transplacental passage of T. pallidum to the foetus and by blood transfusion. The serological diagnosis of syphilis is performed demonstrating the presence of significant levels of specific T. pallidum antibodies in the patient serum sample. The reference method used is the FTA-ABS technique that allows the detection of both IgG and IgM. However, its execution is laborious and the interpretation of results not simple. Alternative methods have therefore been introduced to simplify the procedure: reaction with lipoidal antigens (the reagin test) or agglutination of erythrocytes coated with specific T. pallidum antigens (hemmagglutination test or TPHA). The TPHA is the preferred technique for screening purposes, since that it detects specific IgG and IgM.;Species Reactivity:Bacteria;Application:qualitative;Storage:Unopened Kit: Store at 2 - 8°C. Do not use past kit expiration date. Opened/Reconstituted Reagents: TMB Solution A; TMB Solution B; TMB Stop Solution; Wash Buffer; HRP-conjugate antibody The above mentioned reagents should be stored for up to 1 month at 2 - 8°C. Microplate Wells: Return unused wells to the foil pouch containing the desiccant pack, reseal along entire edge of zip-seal. May be stored for up to 1 month at 2 - 8°C.;Usage:For Lab Research Use Only;Detection Principle:Sandwish ELISA;