Cat#:ABRPA-0454;Product Name:Active Recombinant Cynomolgus Monkey RIPK1 Protein(GST Tag);Synonym:RIPK1, RIP, RIP1, RIP-1, receptor interacting serine/threonine kinase 1;Background:Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an enzyme which is encoded by the RIPK1 gene, which is located on chromosome 6. RIPK1 is known to have function in a variety of cellular pathways related to both cell survival and death.RIPK1 has been primarily studied in the context of TNFR signaling, RIPK1 is also activated in response to diverse stimuli.It has been shown that cell survival can be regulated through different RIPK1-mediated pathways that ultimately result in the expression of NF-kB, a protein complex known to regulate transcription of DNA and thus, related to survival processes.;Description:Recombinant cynomolgus monkey RIPK1 protein produced from baculovirus in Sf9 insect cells, was fused with a GST tag at N terminal. RIPK1 recombinant was purified using our unique purification methods.;Source:Sf9 insect cells;AA Sequence:1-326;Molecular Characterization:62kDa;Purity:For specific information on a given lot, see related product datasheet.;Endotoxin:<1.0 EU per μg of the recombinant RIPK1 protein as determined by the LAL method;Bioactivity:Active;Formulation:Liquid Solution;Stability:Active Recombinant Cynomolgus Monkey RIPK1 is stable up to 1 year from date of receipt at -70℃;Host Species:Cynomolgus Monkey;Application:Kinase Assay, WB;Storage:Store Recombinant Cynomolgus Monkey RIPK1 is stable up to 1 year from date of receipt at -70℃;Usage:For Lab Resarch Use Only!;Supplied in:50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.;References:Expression and genetic polymorphism of necroptosis related protein RIPK1 is correlated with severe hepatic ischemia-reperfusion injury and prognosis after hepatectomy in hepatocellular carcinoma patients. Yao C, et al. Cancer Biomark, 2017 Jul 19. PMID 28759952;
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an enzyme which is encoded by the RIPK1 gene, which is located on chromosome 6. RIPK1 is known to have function in a variety of cellular pathways related to both cell survival and death.RIPK1 has been primarily studied in the context of TNFR signaling, RIPK1 is also activated in response to diverse stimuli.It has been shown that cell survival can be regulated through different RIPK1-mediated pathways that ultimately result in the expression of NF-kB, a protein complex known to regulate transcription of DNA and thus, related to survival processes.
Description:
Recombinant cynomolgus monkey RIPK1 protein produced from baculovirus in Sf9 insect cells, was fused with a GST tag at N terminal. RIPK1 recombinant was purified using our unique purification methods.
Source:
Sf9 insect cells
AA Sequence:
1-326
Molecular Characterization:
62kDa
Purity:
For specific information on a given lot, see related product datasheet.
Endotoxin:
<1.0 EU per μg of the recombinant RIPK1 protein as determined by the LAL method
Bioactivity:
Active
Formulation:
Liquid Solution
Stability:
Active Recombinant Cynomolgus Monkey RIPK1 is stable up to 1 year from date of receipt at -70℃
Store Recombinant Cynomolgus Monkey RIPK1 is stable up to 1 year from date of receipt at -70℃
References:
Expression and genetic polymorphism of necroptosis related protein RIPK1 is correlated with severe hepatic ischemia-reperfusion injury and prognosis after hepatectomy in hepatocellular carcinoma patients. Yao C, et al. Cancer Biomark, 2017 Jul 19. PMID 28759952